He has to limit alcohol consumption, eat meals rich in calcium and iron and unfold his protein consumption throughout every day. Certain meals, particularly when restricted for a very long time, becomes what is known as set off meals.

The exception to the rule is the DOT1 household, members of which methylate K79 in the globular area of histone H3 and which are structurally not related to SET-area proteins four - 6 Current work means that SET-domain-containing proteins methylate a few proteins in addition to histones (see later)